Name: GP-1
Location: Extracellular
Function: Ligand binding or carrier
Description: GP-1 is the peripheral membrane glycoprotein. It has 4 to 11 potential N-linked glycosylation sites. The GP-1 portion of the glycoprotein spike is responsible for initial binding to cellular receptors, and antibodies directed to epitopes on GP-1 can block viral binding and neutralize viral infectivity. GP-1 has only been described for LCMV, Lassa virus, Oliveros virus, and Mobala virus.
References:
Buchmeier, MJ. 2002. Arenaviruses: Protein structure and function. In: MBA Oldstone (ed.), Arenaviruses I. The epidemiology, molecular and cell biology of arenaviruses, pp. 159-173. Springer-Verlag.
References:
Meyer BJ, de la Torre JC, Southern PJ. 2002. Arenaviruses: Genomic RNAs, transcription, and replication. In: MBA Oldstone (ed.), Arenaviruses I. The epidemiology, molecular and cell biology of arenaviruses, pp. 139-175. Springer-Verlag.