Data Resources

The Pathogen Portal provides access to high quality genomic, transcriptomic, proteomic, pathway and general data for select pathogens that is curated or stored by Virginia Bioinformatics Institute. This data is frequently updated and focuses on CDC category A or B pathogens, NIAID priority category A, B, or C pathogens and or MARCE (Middle Atlantic Regional Center of Excellence in Biodefense and Emerging Infectious Diseases) targeted pathogens.

Pathway Data: The MINet information is focused on a high level description of molecular and cellular objects and their interactions, including phenomena not known at biochemical detail. It emphasizes thoroughness of curatorial attribution and cross-referencing to external databases and ontology systems.

Pathogen Information Data: A vast amount of information about animal and plant pathogens has been acquired, stored, and displayed in varied formats through different resources, both electronic and otherwise, some accessible through the Internet. We have organized this information and presented it in both human and machine-readable format for data exchange. Detailed documents are available for 21 pathogens deemed of high priority with regard to public health and national biological defense.

Genomic Data: As one of the eight Bioinfomatics Resource Centers funded by the National Institutes of Health through the National Institute of Allergy and Infectious Diseases, PATRIC's goal is to provide a comprehensive and accurate web-based resource for genomic and associated information on a number of important human pathogens.

Proteomic Data: The goal of the The Proteomics Data Center at the Virginia Bioinformatics Institute (VBI) is to provide a single, integrated proteomics information repository, user interfaces, and necessary analysis tools for the seven Proteomics Research Centers (PRPs) funded through the National Institute of Allergy and Infectious Diseases(NIAID).

Islander: Database of Genomic Islands. Bacterial and archaeal chromosomes often contain one or more mobile DNAs known as genomic islands. These are important agents of microbial evolution because they carry rapidly-evolving genes promoting specialized phenotypes, such as pathogenicity and mutualism. Most often the integration sites are in genes for tRNAs or other small RNAs; this observation is the basis for an algorithm we developed to find islands de novo in genome sequences (Mantri and Williams, 2004. Nucleic Acids Res. 32: D55-58). Here we present the islands identified this way.

Transriptomic Data: to be added later